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    § Federal grant opportunity · RFA-HG-27-010

    Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)

    National Institutes of Health is accepting applications for Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed). The deadline is December 14, 2026 and the published award range is $800K.

    Key facts

    Funder
    National Institutes of Health
    Application deadline
    December 14, 2026
    Award range
    $800K
    Eligibility
    nonprofits non higher education with 501c3, independent school districts, public and state institutions of higher education, special district governments, city or township governments, nonprofits non higher education without 501c3, other native american tribal organizations, for profit organizations other than small businesses, small businesses, federally recognized native american tribal governments, public and indian housing authorities, state governments, county governments, private institutions of higher education, other
    Geography
    United States
    Focus areas
    Health
    Opportunity number
    RFA-HG-27-010

    Program overview

    The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to develop, apply, and test predictive models and perform integrative analyses to determine the impact of genomic variation on genome function. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers also will collaborate with other consortium components to guide and optimize IGVF experimental design, to provide analytical expertise and support for consortium-wide efforts, and to develop and execute shared analysis strategies to meet consortium goals.

    How to apply

    1. Confirm your organization meets the eligibility criteria above.
    2. Read the full funding opportunity announcement from National Institutes of Health.
    3. Draft your narrative against the funder's stated priorities and review criteria.
    4. Submit before December 14, 2026, allowing time for registration and validation.

    View the official funding announcement

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