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    § Federal grant opportunity · RFA-RM-27-016

    Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)

    National Institutes of Health is accepting applications for Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed). The deadline is November 23, 2026 and the published award range is Award amount not published.

    Key facts

    Funder
    National Institutes of Health
    Application deadline
    November 23, 2026
    Award range
    Award amount not published
    Eligibility
    special district governments, nonprofits non higher education with 501c3, small businesses, other, federally recognized native american tribal governments, public and indian housing authorities, other native american tribal organizations, state governments, public and state institutions of higher education, nonprofits non higher education without 501c3, private institutions of higher education, city or township governments, county governments, independent school districts, for profit organizations other than small businesses
    Geography
    United States
    Focus areas
    Health
    Opportunity number
    RFA-RM-27-016

    Program overview

    The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and disease-relevant cellular senescence signatures (“senotypes”) and associated biomarkers, and will investigate their functional consequences in human health and disease. DVCs are expected to generate and contribute high-quality molecular, cellular, and spatial datasets (including relevant metadata and documentation) and to use complementary experimental systems, as appropriate, to validate senotypes/biomarkers and characterize responses to senescence-associated perturbations or senotherapeutic approaches. DVC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).

    How to apply

    1. Confirm your organization meets the eligibility criteria above.
    2. Read the full funding opportunity announcement from National Institutes of Health.
    3. Draft your narrative against the funder's stated priorities and review criteria.
    4. Submit before November 23, 2026, allowing time for registration and validation.

    View the official funding announcement

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