§ Federal grant opportunity · RFA-RM-27-007
Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed)
National Institutes of Health is accepting applications for Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed). The deadline is November 23, 2026 and the published award range is Award amount not published.
Key facts
- Funder
- National Institutes of Health
- Application deadline
- November 23, 2026
- Award range
- Award amount not published
- Eligibility
- public and state institutions of higher education, public and indian housing authorities, state governments, other, county governments, city or township governments, special district governments, federally recognized native american tribal governments, private institutions of higher education, nonprofits non higher education with 501c3, for profit organizations other than small businesses, other native american tribal organizations, small businesses, nonprofits non higher education without 501c3, independent school districts
- Geography
- United States
- Focus areas
- Health
- Opportunity number
- RFA-RM-27-007
Program overview
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit the development of innovative senescence technologies (SenTecs), or the adaptation of existing technologies focused on identification, characterization and understanding the biological consequences of senescent cell (SnC) heterogeneity in the context of the tissue environments and secretomes to facilitate novel strategies for modulating SnCs in vivo and for predicting the outcomes of targeting SnCs in human aging and in disease conditions. These are five-year, milestone-driven awards consisting of two phases. The first two years constitute the UG3 phase and are focused on SenTec development and demonstration of technology feasibility. The following 3-years is the SenTec application UH3 phase where SenTecs continue to be optimized, refined and validated. In the final year of the UH3 award, SenTecs will undertake a demonstration project conducted in a collaborative effort within SenNet to provide further validation of the proposed SenTec. Applicants are required to submit both UG3 and UH3 projects together when responding to this NOFO. Transition from the UG3 to UH3 phases is not automatic and will occur only after administrative review of each SenTec at the close of Year 2 of the award.
How to apply
- Confirm your organization meets the eligibility criteria above.
- Read the full funding opportunity announcement from National Institutes of Health.
- Draft your narrative against the funder's stated priorities and review criteria.
- Submit before November 23, 2026, allowing time for registration and validation.
Related grant opportunities
- Cellular Senescence Network (SenNet): SenNet Data Coordination and Integration Center (SenNet DCIC) (UM1 Clinical Trials Not Allowed)
- NIJ FY 2026 Research and Evaluation on School Safety
- Charles B. Rangel Graduate Foreign Affairs Fellowship Program Administration Grant
- 2027 Thomas R. Pickering Foreign Affairs Fellowship Program Administration Grant
- 2027 Thomas R. Pickering Foreign Affairs Fellowship Program Selection Grant
Find every grant your organization qualifies for
Mavenly scores this opportunity against your mission, geography, and funding history — then drafts the proposal with you and tracks the deadline through submission and reporting.