§ Federal grant opportunity · RFA-AI-28-012
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
National Institutes of Health is accepting applications for Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed). The deadline is January 29, 2027 and the published award range is Award amount not published.
Key facts
- Funder
- National Institutes of Health
- Application deadline
- January 29, 2027
- Award range
- Award amount not published
- Eligibility
- special district governments, federally recognized native american tribal governments, nonprofits non higher education without 501c3, public and state institutions of higher education, other, private institutions of higher education, county governments, other native american tribal organizations, for profit organizations other than small businesses, city or township governments, independent school districts, nonprofits non higher education with 501c3, small businesses, state governments, public and indian housing authorities
- Geography
- United States
- Focus areas
- Health
- Opportunity number
- RFA-AI-28-012
Program overview
The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. To meet this need, the Centers will refine well validated human tissue models studying infectious diseases to a level consistent with regulatory qualifications that will promote their adoption for use by product developers, supporting regulatory acceptance.
How to apply
- Confirm your organization meets the eligibility criteria above.
- Read the full funding opportunity announcement from National Institutes of Health.
- Draft your narrative against the funder's stated priorities and review criteria.
- Submit before January 29, 2027, allowing time for registration and validation.
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