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    § Federal grant opportunity · RFA-DK-27-122

    Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)

    National Institutes of Health is accepting applications for Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required). The deadline is November 17, 2026 and the published award range is Award amount not published.

    Key facts

    Funder
    National Institutes of Health
    Application deadline
    November 17, 2026
    Award range
    Award amount not published
    Eligibility
    private institutions of higher education, special district governments, county governments, public and indian housing authorities, small businesses, federally recognized native american tribal governments, state governments, nonprofits non higher education without 501c3, other native american tribal organizations, nonprofits non higher education with 501c3, city or township governments, independent school districts, for profit organizations other than small businesses, public and state institutions of higher education, other
    Geography
    United States
    Focus areas
    Health
    Opportunity number
    RFA-DK-27-122

    Program overview

    The purpose of this NOFO is to continue the Physiology of the Weight Reduced State (POWERS) clinical trial. The goal of POWERS is to understand the physiological processes underlying individual variability in weight regain following weight loss due to a lifestyle intervention. The continuation of POWERS will allow for the completion of the ongoing clinical trial and to conduct analysis of collected data and biospecimens. This NOFO invites a single source application from the Data Coordinating Center for the POWERS consortium. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application will be peer-reviewed, and only meritorious application(s) will be considered for funding.

    How to apply

    1. Confirm your organization meets the eligibility criteria above.
    2. Read the full funding opportunity announcement from National Institutes of Health.
    3. Draft your narrative against the funder's stated priorities and review criteria.
    4. Submit before November 17, 2026, allowing time for registration and validation.

    View the official funding announcement

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