§ Federal grant opportunity · RFA-HG-27-013
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
National Institutes of Health is accepting applications for GREGoRi Innovation Projects (U01 Clinical Trial Optional). The deadline is October 30, 2026 and the published award range is $3 – $500K.
Key facts
- Funder
- National Institutes of Health
- Application deadline
- October 30, 2026
- Award range
- $3 – $500K
- Eligibility
- Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
- Geography
- United States
- Focus areas
- Health
- Opportunity number
- RFA-HG-27-013
Program overview
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
How to apply
- Confirm your organization meets the eligibility criteria above.
- Read the full funding opportunity announcement from National Institutes of Health.
- Draft your narrative against the funder's stated priorities and review criteria.
- Submit before October 30, 2026, allowing time for registration and validation.
Related grant opportunities
- GREGoRi Technology Integration Center (U01, Clinical Trials Optional)
- GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
- RESTORE Act Direct Component - Non-Construction Activities
- RESTORE Act Centers of Excellence Research Grants Program
- RESTORE Act Direct Component – Construction and Real Property Acquisition Activities
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